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Lakesis from Codif:
Awakens youth proteins in the skin Lakesis is obtained from crystal drops collected on the Mastic Tree (Pistacia Lentiscus). Lakesis increases the synthesis of KLOTHO and FOXO youth proteins, which decrease as we get older starting at just 30 years of age! Activating youth proteins provides a new and exciting anti-ageing strategy. |
 What
is Lakesis?On the island of Chios, Greece, ancient trees produce a resin which drops from the trunk into the shape of tears. Tears of Chios have endless cosmetic and medicinal properties. Once crystallized, they are used for the production of Lakesis. Lakesis increases the synthesis of two youth proteins: KLOTHO and FOXO. Once solidified, these drops  take on a crystalline shape and are known as ‘crystal tears’.
The importance of Youth Proteins FOXO and KLOTHO FOXO protein is located directly inside the nucleus, the “nuclear” form of FOXO activates the transcription of genes involved in cellular detoxification and the repair of DNA damage. The FOXO protein becomes phosphorylated by the AKT factor and loses its properties. Activation of the AKT factor increases with age. A protein which is able to inhibit AKT activation and therefore maintain FOXO inside the cell nucleus was identified in 1997, called KLOTHO. KLOTHO protein is involved in a large number of signaling pathways leading to the reestablishment of optimal cellular function. Codif has shown that its rate of expression is directly linked to the age of human fibroblasts. The decrease in KLOTHO expression starts very early, from roughly 30 years of age! >> INCREASING KLOTHO SYNTHESIS IN FIBROBLASTS REPRESENTS A NEW STRATEGY TO COMBAT SKIN AGING. Overview of Lakesis attributes * "54 year old fibroblasts recover characteristics of 37 year old fibroblasts." * Cellular detoxification processes are reactivated. * Cellular activity is increased. * The dermis is redensified with fibrillin and collagen fibres. * Skin looks younger, thicker and facial contours appear to be redrawn. >> Download the Lakesis brochure. |
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